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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76976 | Tixagevimab | ||
Tixagevimab (AZD8895)为人源单克隆抗体,针对SARS-CoV-2的受体结合结构域(RBD)具有靶向性。该抗体通过结合RBD及S糖蛋白外域,进而阻断S糖蛋白与受体的结合,展示出对SARS-CoV-2的中和活性。 | |||
T80581 |
Plutavimab
COVI-AMG,STI-2020 |
SARS-CoV | Microbiology/Virology |
Plutavimab为针对SARS-CoV-2 Spike (S) 糖蛋白受体结合域 (RBD) 的人源化IgG1-κ型单克隆抗体。 | |||
T76923 | Beludavimab | ||
Beludavimab (BMS 4182137; VIR 7832) 是一种针对 SARS-CoV-2刺突糖蛋白的单克隆抗体。Beludavimab 与重组刺突蛋白受体结合域 (S-RBD) 结合,EC50值为 14.9 ng/mL,Kd 为 0.21 nM。 | |||
T74426 | Ogalvibart | ||
Ogalvibart (C-135-LS)为人源化抗SARS-CoV-2单克隆抗体(IgG1型),能够与SARS-CoV-2的S蛋白RBD紧密结合。当与C144LS以1:1比例联合使用时,Ogalvibart显示出优异的预防活性,能有效预防恒河猴疾病模型中COVID-19的发展。 |
Cat. No. | Product Name | Species | Expression System |
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TMPK-00439 |
SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated
S protein RBD,S glycoprotein<... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu... | |||
TMPK-00912 |
SARS Spike RBD Protein (His & Avi), Biotinylated
S glycoprotein RBD,S pro... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number... | |||
TMPK-00434 |
SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated
S protein RBD,S glycoprotein<... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 51.7 kDa and the accession ... | |||
TMPK-00911 |
SARS Spike RBD Protein (His & Avi)
S protein RBD,Spike protein R... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number is P59594. | |||
TMPK-00437 |
SARS-COV-2 Spike RBD Protein (His & Avi)
S glycoprotein RBD,Spike... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is A0A6G7... | |||
TMPY-06885 |
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
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The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of... |